Publications
2019
Lessons Learned from the metastatic castration-resistant phase 1 of EPI-506, a first-generation androgen receptor N-terminal domain inhibitor. Genitourinary Cancers Symposium 2019. (Abstract# 257).
. Read More > Genitouronary Cancers Symposium Poster
2017
Efficacy, safety, tolerability, and pharmacokinetics of EPI-506 (ralaniten acetate), a novel androgen receptor (AR) N-terminal domain (NTD) inhibitor, in men with metastatic castration-resistant prostate cancer (mCRPC) progressing after enzalutamide and/or abiraterone. ASCO Annual Meeting 2017(Abstract# 5032).
. Read More > ASCO Poster
2016
Targeting the N-terminal Domain of the Androgen Receptor: A New Approach for the Treatment of Advanced Prostate Cancer. The Oncologist 2016
. Read More >Sintokamide A is a novel antagonist of androgen receptor that uniquely binds activation function-1 in its amino-terminal domain. JBC 2016
. Read More >An imaging agent to detect androgen receptor and its active splice variants in prostate cancer. JCI Insight 2016
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